isaiah.grant
isaiah.grant Feb 17, 2026 • 10 views

Endoplasmic Reticulum Practice Quiz: Test Your AP Biology Knowledge

Hey there, future AP Bio stars! 👋 Ever get tangled up trying to remember the difference between the smooth and rough ER? Or how proteins get where they need to go? 🤔 Don't worry, we've all been there! This quick quiz will help you nail down the key concepts. Let's boost your knowledge and ace that test! 💪
🧬 Biology

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ashley_acosta Dec 28, 2025

📚 Topic Summary

The endoplasmic reticulum (ER) is a network of membranes found within eukaryotic cells. It plays a crucial role in protein synthesis, folding, modification, and transport, as well as lipid and steroid synthesis. There are two main types: the rough ER (RER), studded with ribosomes for protein synthesis, and the smooth ER (SER), involved in lipid metabolism, detoxification, and calcium storage. Understanding their individual functions and how they work together is essential for understanding cellular function.

🧪 Part A: Vocabulary

Match the terms with their definitions:

  1. Terms: Ribosomes, Lumen, Vesicles, Detoxification, Protein Folding
  2. Definitions:
    1. Modifying a protein to achieve its functional shape.
    2. Small membrane-bound sacs that transport substances within the cell.
    3. The process of removing toxic substances from the body.
    4. Cellular structures responsible for protein synthesis.
    5. The interior space of the endoplasmic reticulum.

Matching Answers:

  • Ribosomes - d
  • Lumen - e
  • Vesicles - b
  • Detoxification - c
  • Protein Folding - a

🧬 Part B: Fill in the Blanks

The [Rough] ER is distinguished by the presence of [ribosomes] on its surface, giving it a 'rough' appearance. These ribosomes are responsible for synthesizing [proteins] that are then processed within the ER lumen. In contrast, the [smooth] ER lacks ribosomes and is primarily involved in lipid [synthesis] and detoxification.

🤔 Part C: Critical Thinking

Imagine a cell that is actively producing steroid hormones. Would you expect this cell to have a large amount of rough ER or smooth ER? Explain your reasoning.

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